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Melanocytic Tumors
Primary neoplasms arising from leptomeningeal melanocytes.
Subtypes2
Grade Range
G1G3
Subtypes
Meningeal melanocytoma
WHO Grade 1
Benign leptomeningeal tumor.
Diagnostic Molecular Markers
GNAQ or GNA11 mutations
Locations:
Meningeal melanoma
WHO Grade 3
Malignant leptomeningeal tumor.
Diagnostic Molecular Markers
GNAQ, GNA11, PLCB4
Locations:
Primary Locations
Clinical Note
Grading and diagnostic criteria listed here are based strictly on the 2021 WHO Classification of Tumours of the Central Nervous System (5th Edition). Many entities now require integrated phenotypic and genotypic characterization for a final diagnosis.