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Pineal Tumors
Neoplasms arising in the pineal parenchymal organ or specialized local neuroepithelium.
Subtypes3
Grade Range
G1G2G3G4
Subtypes
Pineoblastoma
WHO Grade 4
Aggressive tumor invading the posterior third ventricle and tectum.
Diagnostic Molecular Markers
RB1 lossDICER1 mutations
Locations:
Papillary tumor of the pineal region (PTPR)
WHO Grade 2WHO Grade 3
Originates near the posterior commissure.
Diagnostic Molecular Markers
PTEN mutations
Locations:
Primary Locations
Clinical Note
Grading and diagnostic criteria listed here are based strictly on the 2021 WHO Classification of Tumours of the Central Nervous System (5th Edition). Many entities now require integrated phenotypic and genotypic characterization for a final diagnosis.