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Choroid Plexus Tumors
Primary intraventricular papillary neoplasms originating from the choroid plexus epithelium.
Subtypes3
Grade Range
G1G2G3
Subtypes
Choroid plexus papilloma (CPP)
WHO Grade 1
Benign papillary tumor. Typically found in lateral ventricles in children and fourth ventricle in adults.
Locations:
Atypical choroid plexus papilloma (aCPP)
WHO Grade 2
Displays elevated mitotic activity compared to standard CPP.
Locations:
Choroid plexus carcinoma (CPC)
WHO Grade 3
Malignant variant. Presents as a massive bulky lesion in infants.
Diagnostic Molecular Markers
TP53 mutation (often Li-Fraumeni syndrome)
Locations:
Primary Locations
Clinical Note
Grading and diagnostic criteria listed here are based strictly on the 2021 WHO Classification of Tumours of the Central Nervous System (5th Edition). Many entities now require integrated phenotypic and genotypic characterization for a final diagnosis.